Description
What is it
Pirandai — Cissus quadrangularis, the square-stemmed creeper of the grape family — is one of the most storied herbs of Siddha and Ayurvedic tradition. Sanskrit named it Asthisamharaka, “that which keeps the bones from harm,” and Vajravalli, “the diamond creeper”; Hindi calls it Hadjod, the bone-joiner. In Tamil homes it has always been both food and medicine — the young stems cooked into thuvaiyal and chutney. We take the raw whole stem, cleaned and dried in the Western Ghats tradition, and present it single-ingredient in a vegetarian capsule — the classical bone-and-joint herb, without preparing the fibrous stem yourself.
What Makes This Different
- Raw whole stem, single ingredient. Raw whole-stem Cissus quadrangularis powder — no fillers, binders, flow agents or extract dilution.
- Stem, the part tradition uses. Pirandai’s bone-and-joint reputation rests on the fleshy quadrangular stem; we use the stem, and say so — not a root or leaf shortcut.
- The fibrous stem, made effortless. Raw Pirandai is stringy and sharp to handle fresh; the capsule delivers it clean, with none of the kitchen preparation.
- Certified base: FSSAI Central Licensed, GMP compliant, ISO 22000.
What It Does
- The classical bone-and-joint herb. For centuries Siddha and Ayurveda have turned to Pirandai for bone and joint strength — its very names, Asthisamharaka and Hadjod, record that reputation across languages.
- Studied for bone-forming activity. Animal and laboratory studies have examined the stem’s influence on bone-forming cell (osteoblast) activity and bone-mineral density, with a small human pilot adding early clinical observation (animal / in vitro / small human pilot).
- Traditionally valued for joint comfort. Tradition has long reached for Pirandai for supple, comfortable joints; laboratory work has recorded anti-inflammatory activity in the stem (in vitro).
- A traditional Tamil digestive stem. Eaten as thuvaiyal and chutney for generations to support digestion and appetite; laboratory studies have also examined the stem’s gastroprotective activity (animal / in vitro).
- Emerging angle — resveratrol and antioxidants. The stem naturally contains vitamin C, carotenoids and the polyphenol resveratrol, and lab assays record notable free-radical-scavenging activity — an active area of interest (in vitro).

How to Take It
Take one veg capsule twice daily with water, with or after food, as part of your daily routine — in keeping with Pirandai’s long tradition of being taken as part of a meal. Best enjoyed steadily rather than as a short course. If you are pregnant or breastfeeding, giving it to a child, or taking prescription medication, consult a healthcare professional before starting any new supplement.
Disclaimer
Yogis Herbs Pirandai Capsules are a herbal food supplement, not a medicine, and are not intended to diagnose, treat, cure or prevent any disease. Those who are pregnant or breastfeeding, children, and anyone on medication should consult a healthcare professional before use. These statements have not been evaluated by the Food and Drug Administration. Individual results vary; enjoy as part of a balanced diet and healthy lifestyle.
References
- Singh N. et al. (2013). Clinical evaluation of Cissus quadrangularis as osteogenic agent in maxillofacial fracture: A pilot study. PMC4784127. Human pilot. Notes the herb’s classical citation as a bone tonic (Bhava Prakasha, Chakra Dutta) and evaluates its osteogenic effect. https://pmc.ncbi.nlm.nih.gov/articles/PMC4784127/
- An Overview of the Osteogenic Potential of the Indian Herb Cissus quadrangularis (Veldt Grape) (2024). Review (animal / in vitro). Summarises stem constituents (ketosteroids, calcium, resveratrol) and their studied influence on bone-forming activity. https://www.researchgate.net/publication/386273358
- Chidambara Murthy K.N. et al. (2003). Antioxidant and antimicrobial activity of Cissus quadrangularis L. Journal of Medicinal Food, 6(2):99-105. In vitro (stem). The ethyl acetate stem fraction showed roughly 65% antioxidant activity (beta-carotene model) and 62% (DPPH). https://pubmed.ncbi.nlm.nih.gov/12935320/
- Cissus quadrangularis: a pharmacological review. Research Journal of Pharmacognosy & Phytochemistry (2019). Review (animal / in vitro). Documents gastroprotective (proton-pump inhibition) and antioxidant activity of the stem. https://rjpponline.org/HTML_Papers/Research%20Journal%20of%20Pharmacognosy%20and%20Phytochemistry__PID__2019-11-3-4.html
- Simultaneous estimation of quercetin and trans-resveratrol in Cissus quadrangularis (2023). PMC10301570. Analytical. Identifies resveratrol, quercetin, beta-sitosterol and quadrangularins A-C among the plant’s constituents. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10301570/




